Docusate calcium, docusate potassium, and docusate sodium
Trade Names:
Colace, Diocto-K, Dioctyl Calcium Sulfosuccinate, Dioctyl Potassium Sulfosuccinate, Dioctyl Sodium Sulfo-succinate, Diosuccin, DOK-250, Doxinate, Duosol, Laxinate 100, Regular SS, Stulex
Type of Drug:
Docusate calcium, docusate potassium, and docusate sodium belong to a class of drugs called stool softeners. They are used to treat constipation.
How Drug Works:
Docusate calcium, docusate potassium, and docusate sodium work to increase the amount of water that the stool absorbs as it passes through the intestines. This softens the stool.
How Drug Is Given:
Docusate calcium/potassium/sodium are soft-gel caps that are given by mouth. The dose is usually standard, but if you still have trouble with hard stools, your doctor may increase the dose or give you a different medicine. Do not take mineral oil if you are taking docusate calcium/potassium/sodium. It may cause the mineral oil to be absorbed into your body. Keep the medicine in a tightly closed container away from heat and moisture and out of the reach of children and pets.
How Should I Take This Drug?
Take this drug exactly as directed by your doctor. If you do not understand the instructions, ask your doctor or nurse to explain them to you.

Read the following information. If you do not understand it or if any of it causes you special concern, check with your doctor.
Before taking this drug, tell your doctor if you are taking any other prescription or over-the-counter drugs, including vitamins and herbals.

Should I avoid any other medicines, foods, alcohol, and/or activities?
Your prescription and nonprescription medicines may interact with other drugs, causing harm. Certain foods or alcohol can also interact with drug products. Never begin taking a new medicine"prescription or nonprescription"without asking your doctor or nurse if it will interact with alcohol, food, or other medicines. Some drug products can cause drowsiness and affect activities such as driving.
To prevent constipation, try to drink 2 to 3 quarts of fluid a day, increase the amount of bran, fruits, and vegetables in your diet (try to eat 5 servings of fruits and vegetables daily), eat vegetable fiber or cereal, and do light exercise as much as you can.
Docusate calcium, docusate potassium, and docusate sodium are not absorbed into the body, so there are no side effects.
Take with full glass of water, or with juice if you do not like the taste.
Docusate calcium, docusate potassium, and docusate sodium may take up to 3 days to soften the stool.
Docusate calcium is useful in preventing straining-at-stool and useful in preventing constipation, but it is not effective as treatment once constipation has occurred.
Stop drug if abdominal cramping occurs.

Tell all the doctors, dentists, and pharmacists you visit that you are taking this drug.
  • Most of the following side effects probably will not occur.
  • Your doctor or nurse will want to discuss specific care instructions with you.
  • They can help you understand these side effects and help you deal with them.
Side effects can occur in some patients. Tell your doctor or nurse if you develop any problems.

FDA Approval: Yes